{"id":7810,"date":"2022-05-03T20:57:11","date_gmt":"2022-05-04T01:57:11","guid":{"rendered":"https:\/\/americacellbank.com.co\/sin-categorizar\/benefits-of-stem-cells-for-the-treatment-of-pulmonary-fibrosis"},"modified":"2024-09-04T16:56:20","modified_gmt":"2024-09-04T21:56:20","slug":"benefits-of-stem-cells-for-the-treatment-of-pulmonary-fibrosis","status":"publish","type":"post","link":"https:\/\/americacellbank.com.co\/en\/blog\/benefits-of-stem-cells-for-the-treatment-of-pulmonary-fibrosis\/","title":{"rendered":"Benefits of stem cells for the treatment of pulmonary fibrosis"},"content":{"rendered":"<p>Pulmonary fibrosis is an idiopathic disease.<br \/>\nIt presents as a chronic fibrosing interstitial pneumonia.<br \/>\nIt is progressive and of unknown etiology.<br \/>\nIt occurs mostly in older adults with an average age of approximately 55-75 years.<br \/>\nIt only involves the lungs, where it enlarges and inflames fibroblasts and modifies the extracellular matrix.<br \/>\nThis lung disease is fatal.<br \/>\nIt has a survival time of 3-5 years.<br \/>\nUntil now, the drugs <strong>pirfenidone and nintedanib<\/strong> have been the only drugs that have allowed prolonging the time to stop the progression and deterioration of this disease.<br \/>\nThey also inhibit the deterioration of lung function and increase survival in humans.<br \/>\nHowever, they do not provide a definitive cure and are not well tolerated.<br \/>\nIn the <strong><a class=\"_ps2id\" href=\"https:\/\/www-ncbi-nlm-nih-gov.translate.goog\/pmc\/articles\/PMC6299195\/?_x_tr_sl=en&amp;_x_tr_tl=es&amp;_x_tr_hl=es&amp;_x_tr_pto=sc\" target=\"_blank\" rel=\"noopener\" data-ps2id-offset=\"\">scientific-medical review<\/a><\/strong>In the scientific-medical review, it has been proposed to conduct future clinical research to identify the best therapeutic options with the application of <strong><a href=\"https:\/\/www.americacellbank.com.co\/celulas-madre\">stem cells<\/a><\/strong> for the <strong>treatment of pulmonary fibrosis<\/strong>.            <\/p>\n<h2>What are these cells?<\/h2>\n<p>  They are the body&#8217;s collection of blood cells (white blood cells, red blood cells and platelets).<br \/>\nThey are capable of regulating the body&#8217;s immune response.   <\/p>\n<h2>Benefits of cells and their application as a regenerative treatment<\/h2>\n<ul>\n<li>The pluripotency of mesenchymal cells, in combination with their ability to balance immunity, stop inflammation and benefit epithelial tissue regeneration, is timely and shows promise. <strong>There is hope in applying this therapy as an effective treatment<\/strong>for interstitial lung disease.<\/li>\n<li>At present, the application of the cells as a treatment for idiopathic lung disease and other pathologies has been demonstrated to be safe.<\/li>\n<li>It is also believed that transplantation of mesenchymal genetic material, combined with pharmaceutical therapy of antifibrotic drugs (pirfenidone and nintedanib), helps to slow down the fibrotic increase in the cells.<br \/>\nThe mechanisms of action are still not very clear. <\/li>\n<li>The body&#8217;s cells are housed in the soft tissue that surrounds each blood vessel.<br \/>\nBy making a local incision, <strong>the genetic material is obtained<\/strong>.<br \/>\nBioactive molecules and extracellular vesicles are secreted that promote an immediate response in the immune system.  <\/li>\n<li>The cells promote instantaneous regeneration after insertion.<br \/>\nThe application of these cells has great advantages.<br \/>\nThey are <strong>readily available<\/strong> and proliferate easily.  <\/li>\n<li>Through the stem cell, the <strong>epithelial tissue is restored and the inflammation process<\/strong> of the affected cells <strong>is inhibited<\/strong>.<br \/>\nDue to its tissue repairing effect, this implanted material stimulates different growth factors.<br \/>\nFor example, the growth of keratinocytes, hepatocytes, epidermal growth and angiogenesis.  <\/li>\n<li>These cells also act as repair agents and as storers of adenosine triphosphate and internal functions in the recipient cells.<\/li>\n<li>Cell implantation also regulates the adaptive immune system.<br \/>\nIt slows down the maturation of T cells and dendritic cells. <\/li>\n<li>It also inhibits the growth and increase of B cells and killer cell cytotoxicity.<\/li>\n<li>Cells from bone marrow were the first type most commonly used to combat lung diseases.<\/li>\n<\/ul>\n<p>  Finally, we can say that, thanks to the methods and technological advances in reconstructive medicine, the efficacy and safety of stem cell treatment has been proven.<br \/>\nIn recent years, it has been corroborated that they could attenuate different diseases of pulmonary origin.<br \/>\nWith <strong>stem cell transplantation<\/strong>, restoration of the implanted tissues is achieved by means of migratory cells.<br \/>\nHowever, advances continue to be made in the study to improve and expand other therapeutic strategies.<br \/>\nThe goal is to obtain a greater achievement for the treatment of the disease.<br \/>\nThe results are promising, but not definitive. <strong>References<\/strong><a href=\"https:\/\/www-ncbi-nlm-nih-gov.translate.goog\/pmc\/articles\/PMC6299195\/?_x_tr_sl=en&amp;_x_tr_tl=es&amp;_x_tr_hl=es&amp;_x_tr_pto=sc\" target=\"_blank\" rel=\"noopener\">:https:\/\/www-ncbi-nlm-nih-gov.translate.goog\/pmc\/articles\/PMC6299195\/<\/a>     <\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pulmonary fibrosis is an idiopathic disease. It presents as a chronic fibrosing interstitial pneumonia. It is progressive and of unknown etiology. It occurs mostly in older adults with an average age of approximately 55-75 years. It only involves the lungs, where it enlarges and inflames fibroblasts and modifies the extracellular matrix. This lung disease is [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":7272,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[13,52],"tags":[],"class_list":["post-7810","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","category-research"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Treatment of pulmonary fibrosis with stem cells<\/title>\n<meta name=\"description\" content=\"Benefits of stem cells for the treatment of pulmonary fibrosis. 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